Megazeux v2.51 (mzx251.zip, 749k) - This is the last official release of the Megazeux game engine. Some older games may require it to work properly.
The best, most flexible game creation system created for MS-DOS, in my opinion. While it doesn't allow for the best graphics (it's in text mode, but you can edit the ASCII characters), it's extremely flexible, and it also allows Soundblaster music and sound effects. Games are created using a GUI to place various blocks, and programs are written using the built-in OOP Robotic programming language. There are also plenty of user created games available and there were also many webpages dedicated to it. Check it out.
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Games may take awhile to load. CTRL-F12 attempts to speed up game, CTRL-F11 attempts to slow it down.